Dr. Andrea Zendrini to guest edit special issue on nanochemistry in the extracellular space


Dr. Andrea Zendrini, a researcher affiliated with the Center for Colloid and Surface Science in Italy and member of BOW project, is a guest editor for a special issue in the International Journal of Molecular Sciences. Titled Nanochemistry in the Extracellular Space this issue will delve into the intricate physicochemical facets and collective emerging properties of extracellular nanoparticles.

The extracellular space plays a crucial role in regulating physiological processes across diverse organisms. This space is a nanostructured system densely populated with a collection of extracellular nanoparticles. These include biogenic entities such as exomeres, lipoproteins, and extracellular vesicles, acting as mediators for intercellular, cross-species, and cross-kingdom transport processes and communication. Moreover, the extracellular space serves as a conduit for both intentional and unintentional exogenous nano-guests, ranging from drug delivery nanovectors to viruses and pollutants like nanoplastics.

In current research, the focus often narrows down to the isolated examination of individual nanoparticle classes, separating them from the broader context of the extracellular space. This approach inherently imposes limitations on addressing critical questions and hinders a comprehensive understanding of extracellular nanoparticles. Indeed, the dynamism inherent in the extracellular space gives rise to collective phenomena, including the formation of biomolecular coronas, transient aggregation/adsorption, as well as interactions such as kissing and fusion events.

Dr. Andrea Zendrini’s role as the guest editor for the special issue reflects the project’s commitment to advancing research in the field of bionanotechnology. By exploring the extracellular space, this special issue aims to contribute valuable insights to the scientific community, fostering collaboration and innovation in the burgeoning field of nanochemistry. Researchers are invited to actively participate and submit their contributions to this exciting exploration of the extracellular world at the mesoscale level.

A platform for collective exploration

This Special Issue serves as a platform, actively fostering a collective exploration into the physicochemical aspects of the extracellular space and the nanoparticles that inhabit it. The call for submissions extends to research papers, short reports, and captivating up-to-date reviews that significantly contribute to the study of the “collective emerging properties” of extracellular nanoparticles. Examples of topics that align with the vision of this Special Issue include advanced separation and characterization techniques tailored for extracellular nanoparticles, the dynamics of biomolecular coronas on nanoplastics, cutting-edge biosensors, and analytical applications designed specifically for extracellular nanoparticles. Moreover, the exploration extends to the realm of extracellular nanoparticle synthetic and hybrid mimics, shedding light on the interactions between both synthetic and biogenic nanoparticles, and the captivating physical chemistry of viral vectors.

Submission Guidelines

Manuscripts for this special issue should be submitted online at www.mdpi.com by registering and logging in to the website. The call is open until the deadline (31st July), and all submissions passing pre-check will undergo a thorough peer-review process. Accepted papers will be published continuously in the journal and listed together on the special issue website.

For further details on manuscript submission, please visit the Instructions for Authors page.