Nanomaterials and nanodevices constitute a key technology in improving precision medicine and therapeutic approaches. BOW wants to create hybrid magnetic nanoparticles with a membrane surface made from an extracellular vesicle that will advance in those fields. This creation will shape the information contained inside the nanodevice or nanomaterial.

It will proof and set a general and viable paradigm to establish key biomimetic functions including camouflage to the immune system and organ site/tumor targeting to any synthetic nanodevice, while being disruptive as a first example of biogenic nanotechnology. Eventually this new hybrid can be a novel high-risk/high-reward paradigm to impart biological features to toxic technology devices. The natural scale of this kind medicine is as of cellular and subcellular level.

Other major objectives of the project include the production of high-grade extracellular vesicles with biomimetic and organotrophic functions; the synthesis, and functionalization of MBDs; engineering a microfluidic device for the fabrication of extracellular vesicle membrane and the control of biological performances and the nanotoxicity in-vitro, ex-vivo and in-vivo.  If successful, such technology will promote the progress of implantable nanodevices and nanomaterials towards a sustainable production and contributing to strengthen and keep in the lead position of European biotechnology. Also, by impacting the life quality for people.